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Organizing Pericarditis


These micrographs show a thick pericardium. The white dotted lines delineate the fibrosa layer of the parietal pericardium. The tissue above the top dotted line consists of abundant granulation tissue, fibrin deposition and trapped red blood cells, consistent with an organizing inflammatory process undergoing repair. Note the infiltration of the fibrous tissue by mucopolysaccharide material (green) which represents a relatively recent depostion of loose connective tissue. The area below the lower dotted line represents the mediastinal surface of the pericardium which also shows granulation tissue and chronic inflammation.

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