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Glycogen Storage LAMP2

Glycogen storage disease – adult.
The hematoxylin & eosin stain shows marked myocyte hypertrophy with bizarre myocyte nuclei present.  The arrows point at eosinophilic inclusion present in the myocytes.  The intra-sarcoplasmic inclusions are distinctly different from red blood cells (black arrows). 

The lower panel is a positive PAS stain showing the strong reactivity of the carbohydrate moieties with the Schiff reagent (intense pink deposits and granules).
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